Urgent: Pharmacies Must Enroll in CMS Medicare Transaction Facilitator (MTF)

Author: APCI Staff/Wednesday, June 25, 2025/Categories: APCI News

Center for Medicare and Medicaid Services logo

This is a critical reminder that all pharmacies must enroll in the Medicare Transaction Facilitator (MTF) Data Module as soon as possible to remain compliant with new CMS drug refund and data submission requirements starting January 1, 2026.

Failure to enroll may result in delays in receiving Medicare refunds and noncompliance with CMS policy.

✅ Quick Enrollment Checklist:

  1. Sign up for CMS updates:
    CMS Email Updates - https://www.cms.gov/about-cms/web-policies-important-links/email-updates
  2. Review guidance documents:
  3. Register with HARP and request MTF access:
    HARP Registration → Request “MTF Data Module" role  https://harp.cms.gov
  4. Log into the CMS Enterprise Portal:
    portal.cms.gov
  5. Download and sign the MTF User Agreement:
    https://www.cms.gov/files/document/dispensing-entity-mtf-agreement-final.pdf
    Must be signed by your authorized official.
  6. Configure system settings and roles.

Deadline: Act ASAP – Enrollment is open NOW.

For help or questions, contact:
MFPMedicareTransactionFacilitator@cms.hhs.gov

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